Preventing and Dealing with Gout
By Kay Leaman, Health Architect, HealthyDay HealthyLife Gout is a painful form of arthritis that occurs when high levels of uric acid in the blood form crystals and accumulate in and around the joint. However, gout can still occur without high UA levels. The onset of gout is sudden with severe joint pain, redness (feels like the joint is on fire) and is tender to the touch. It often occurs at the base of the big toe, but can affect other joints as well. It is a type of arthritis which creates inflammation in the affected area. Men are more prone than women to have gout. The chances for women increase after menopause. Areas affected are the joints, bursae (sac between bones in joints), tendon sheaths and kidneys. Gout arthritis increases bone fracture risk notably due to low vitamin D levels but also oxidative stress and inflammatory cytokines induced by hyperuricemia. Inflammatory cytokines and oxidative stress can increase bone resorption and decrease bone formation increasing the risk of osteoporosis and bone fractures. Uric acid is produced when purines (a naturally occurring chemical in the body and some foods) are broken down during digestion. UA normally passes through the kidneys and exits through urine without issue. Higher levels due to excess production of UA or failure to eliminate properly triggers the condition. Risk Factors: • Family history • Age and sex • Diet • Obesity (UA levels higher primarily due to lowered elimination) • Medical Conditions: HBP, diabetes, metabolic syndrome,...
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